Released on = June 14, 2007, 9:27 am

Press Release Author = AnaSpec Inc.

Industry = Biotech

Press Release Summary = Drawing on its broad portfolio of MOG (35-55) and other
multiple sclerosis (MS) experimental autoimmune encephalomyelitis (EAE)-related
peptides, AnaSpec has just released its new line of SensoLyteT Anti - MOG ELISA Kits
- the industry's first and only anti-MOG ELISA kits.

Press Release Body = June 12, 2007 - San Jose, CA

Drawing on its broad portfolio of MOG (35-55) and other multiple sclerosis (MS)
experimental autoimmune encephalomyelitis (EAE)-related peptides, AnaSpec has just
released its new line of SensoLyteT Anti - MOG ELISA Kits - the industry's first and
only anti-MOG ELISA kits.

Myelin oligodendrocyte glycoprotein (MOG), a member of the immunoglobulin
superfamily, is expressed exclusively in central nervous system myelin. Recent
studies suggest that MOG may function in the completion, compaction, and maintenance
of myelin in the central nervous system.1 Even though MOG physiological function is
not entirely understood, studies have correlated the immune response of MOG to
autoimmune mediated demyelination in several species.2 MOG is able to induce
encephalitogenic T cell response, autoantibody response, and produce
relapsing-remitting neurological disease with an extensive plaque-like
demyelination.3 Autoantibody response to MOG (35-55) has been observed in multiple
sclerosis (MS) patients and MOG (35-55)-induced experimental autoimmune
encephalomyelitis (EAE) mice;4-10 however, the exact pathological role of anti-MOG
(35-55) autoantibody is not known and is currently under vigorous investigation in
the field.

AnaSpec's SensoLyteT family of anti-MOG (35-55) IgG Quantitative ELISA Kits
(Mouse/rat) are designed to further the research of MS. These kits are optimized to
detect anti-MOG (35-55) mouse/rat IgG and IgG subtypes. Using strips pre-coated with
MOG (35-55) peptide and pre-blocked with BSA, the amount of anti-MOG IgG subtypes in
serum or cerebrospinal fluid can be determined by ELISA and the absorbance read at
450 nm.

Fore more information visit http://www.anaspec.com/products/productcategory.asp?id

Web Site = http://www.anaspec.com

Contact Details = AnaSpec Inc.
ping@anaspec.com